Germany in the 1920s. Martha Dehnert is a petite young girl nicknamed Krümel and grows up in a working-class family in Potsdam. Despite difficult times, she is passionate about her ideals.

[PART 1] Looking, as latest occupational therapy, for a rare wolf wandered into the region from Italy, Andreas's father Franz Marthaler suddenly finds one, but also the wreck of a crashed sports airplane. Andreas swiftly mobilizes his team, to fly the badly wounded pilot to hospital. Once Toni works out it was Martin Hallinger, transporting a donor heart for his little son Linus Hallinger, and had a young woman aboard, utter hast is required, as the rare fitting heart is good only six more hours. After taking Linus to Emilie Hofer, Andreas gets the boy to confide the mystery passenger is Martin's autistic bastard daughter Laura Weiler. Realizing the wolf must have scared her off, Andreas tracks her down, but her paranoia proves dangerous.

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The 'Bulle' is a real tough cop. When he helps a girl being harassed by rockers she steals his car and gun in return. Wanting his stuff back, 'Bulle' follows the girl to the frontier of Holland where she gets caught by German border policemen. The 'Bulle' knocks out the policemen in order to get his gun back having to take the girl, too, as she threatens to be a witness. Thus both are being chased making up a strange friendship.

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Three best friends, Inken, Vicky, and Lena, each have a mind of their own, but they share the same goal: to finally have their first orgasm! But it’s not that easy: amid rivalries, languishing crushes, intimate secrets, and a yeast infection, the girls face many obstacles that will put their friendship to the test.